Filed under: Connections, Emergency, General Musings, Health, NPR, Pandemic, Predictions, Preparedness, Psychic abilities, Science Fiction, tech, Writing stuff | Tags: bats, blogging, Ebola, health, jim downey, NPR, pandemic, predictions, science, Science Fiction, technology, White Nose Syndrome, writing
News item on NPR this afternoon:
The Ebola outbreak in West Africa is the most explosive in history. One reason the virus spread so fast is that West Africa was blindsided. Ebola had never erupted in people anywhere close to West Africa before.
The type of Ebola causing the outbreak — called Zaire — is the deadliest strain. Until this year, it had been seen only in Central Africa, about 2,500 miles away. That’s about the distance between Boston and San Francisco.
How did it get there?
Disease ecologist says scientists don’t know for sure. But they have a top theory: The virus spread through bats.
Many signs point to bats as the main source of Ebola. Scientists have found Ebola antibodies in bat species that are widespread throughout Africa. The virus infects and replicates inside bats, but it doesn’t kill the animals. So bats can easily spread Ebola.
And bats get around. Some can migrate hundreds, even thousands of miles.
… what if a few years ago someone with some limited precognitive ability (either technological or psychic) was able to foresee an Ebola epidemic which made it to the US and then was spread by our native bat population?
And then what if they decided to do something to stop that epidemic before it ever happened … by decimating the bat population?
Yeah, sometimes the ideas I get kinda scare even me.
Filed under: Connections, Emergency, Failure, Flu, General Musings, Government, Health, Pandemic, Plague, Predictions, Preparedness, Science, Science Fiction, Society, Survival, Violence | Tags: blogging, Ebola, Elliot Hannon, fire-flu, Foreign Policy, health, influenza, jim downey, Laurie Garrett, pandemic, predictions, science, Science Fiction, Slate, society, St. Cybi's Well, writing
Sorry for my absence here — I’ve been very busy with a another big project, one which I can’t discuss publicly just yet. But soon.
Without wanting to buy-into the complete panic in some corners about Ebola, here are a couple of very sober articles to consider, which are less about the actual disease and more about what such a pandemic does to the society it hits:
Battling the deadly outbreak of Ebola in Liberia has been a mammoth task for the country’s government and international aid agencies. Over the weekend combating the virus’ spread got even harder when a quarantine center in Monrovia was attacked, and 17 patients being monitored for possible infection fled the medical facility. The Liberian government initially said all of the patients had been relocated to another facility after the West Point health center was looted on Saturday, but later admitted that 17 patients had gone “back into their communities,” the BBC reports.
And this one from last week:
Attention, World: You just don’t get it.
You think there are magic bullets in some rich country’s freezers that will instantly stop the relentless spread of the Ebola virus in West Africa? You think airport security guards in Los Angeles can look a traveler in the eyes and see infection, blocking that jet passenger’s entry into La-la-land? You believe novelist Dan Brown’s utterly absurd description of a World Health Organization that has a private C5-A military transport jet and disease SWAT team that can swoop into outbreaks, saving the world from contagion?
Wake up, fools. What’s going on in West Africa now isn’t Brown’s silly Inferno scenario — it’s Steven Soderbergh’s movie Contagion, though without a modicum of its high-tech capacity.
And from that second article, more to my point:
I myself have received emails from physicians in these countries, describing the complete collapse of all non-Ebola care, from unassisted deliveries to untended auto accident injuries. People aren’t just dying of the virus, but from every imaginable medical issue a system of care usually faces.
That’s the thing — a pandemic is bad enough in its own right, when a disease such as Ebola has a mortality of more than 50% under the best conditions. Consider how much worse the impact will be once the overall public health system collapses due to the death of doctors and nurses, when deliveries can’t be made to restock supplies, when whole cities are quarantined, when people begin to really panic.
That is the horror of a true global pandemic. Like the one in St Cybi’s Well.
Cheery thought, eh?
PS: Two other unrelated things I want to mention. The first is thanks to all who participated in Helping Cassandra – you made a real difference. And the second is just to link to a blog post about some black powder shooting I did this past weekend with some very fun historical guns.
Filed under: Connections, Emergency, Flu, Health, Marketing, movies, NPR, Pandemic, Plague, Predictions, Press, Promotion, Publishing, Science, Science Fiction, Society, Survival, Writing stuff | Tags: Audie Cornish, blogging, CDC, Communion of Dreams, Ebola, flu, Guinea, health, influenza, jim downey, Liberia, movies, Nigeria, NPR, pandemic, predictions, promotion, publishing, quarantine, science, Science Fiction, Sierra Leone, St. Cybi's Well, Thomas Geisbert, Washington Post, WHO, writing
That was a fairly common advertising phrase used to promote books and movies back in the day, referencing spectacular murders and crazed drug orgies. Writers/publishers/moviemakers would try and cynically cash-in on the public attention these events generated by getting their books & movies out quickly.
And recently, it’s a phrase which has been haunting me.
I’ve mentioned previously that sometimes it feels like I am being a bit too prescient about our own future in writing about the alternate timeline of St Cybi’s Well / Communion of Dreams. Like I told a friend this morning:
I’ve made the comment a couple of times, but let me reiterate that it is just plain … creepy? … scary? … to be hearing comments from the CDC and WHO about the spread of this Ebola outbreak, and how it is a virus we don’t really have any treatment for, and how quarantines are necessary to try and control it … *ALL* of which could be coming right out of the SCW stuff I am writing about right now. Blimey. It’s seriously playing with my brain a bit.
Well, at least I know that all the ‘news’ stuff in SCW will have the ring of truth to it …
News? Ring of truth? Try this on for size:
CORNISH: How have past Ebola outbreaks ended, and what do you think needs to be done to end this particular outbreak?
GEISBERT: Outbreaks usually end when the public health agencies are able to come in and quarantine the affected individuals, and, you know, eventually the outbreak runs its course, and it’s over. You know, in central Africa these outbreaks have tended to occur in a very defined geographic area – for example, a village. And the public health agencies, like the World Health Organization and humanitarian aid organizations like Medecins Sans Frontieres, have come in, quarantined that area, and the outbreak has been contained. I think what’s been difficult with West Africa is that it’s so widespread, and it’s occurring simultaneously in so many different areas, that you really stretch that experienced resource thin, and so that’s a huge problem.
How bad is the current outbreak?
Bad — very, very bad. It’s concentrated in three small West African states: Sierra Leone, Liberia and Guinea, where reports of Ebola infections first emerged in February. The outbreak has claimed more than 670 lives and, worryingly, infected medical personnel attempting to stop its spread. A prominent Liberian physician died Sunday.
What’s particularly scary, though, was the recent death of a Liberian man in Lagos, the bustling coastal mega-city in Nigeria, Africa’s most populous country. The man, a consultant for the Liberian government, had traveled from Liberia through an airport in Lome, the capital of Togo, before arriving in Nigeria. The hospital where he died is under lockdown, and the WHO has sent teams to Togo and Nigeria.
So, yeah, the phrase “ripped from today’s headlines” has been kicking around in my head entirely too much the last couple of weeks.
Ah, well, maybe that just means that some large publisher or famous director will knock on my door and hand me a very large chunk of money so I can ignore everything else and finish the book in a few weeks …
Filed under: Amazon, Art, Astronomy, Cassini, Connections, Feedback, Google, Habanero, Humor, Kindle, Marketing, NASA, Pandemic, Plague, Promotion, Publishing, Saturn, Science Fiction, Space, Titan | Tags: Amazon, art, blogging, book design, Cassini, Communion of Dreams, direct publishing, Facebook, feedback, Habaneros, humor, jim downey, Kindle, NASA, pandemic, photography, post-apocalyptic, promotion, reviews, Saturn, Science Fiction, Scorpion Blood, space, Titan
Another item that would likely help get this book moving is a different cover. I understand the imagery now that I’ve read the book, but definitely think it will keep hard-core sci-fi fans from buying a copy (and people do judge books by their covers).
Like I said, every so often a comment to this effect will pop up in a review. And I don’t spend much time thinking about it (and I’m not going to change the cover image at this point), but now and then I wonder just what kind of a cover would appeal to ‘hard-core sci-fi fans’ and still make any kind of sense in relation to the story. Maybe some nice images of Saturn or Titan from the Cassini mission? A depiction of some of the spacecraft (which aren’t described in much detail in the book), or perhaps the Titan Prime space station? Go with a charming post-apocalyptic montage of ruined cities and microphotographs of viruses? To me, none of these would fairly represent the story, and to a certain extent would unnecessarily limit the appeal to only ‘hard-core sci-fi fans’.
But I’m curious what others think. So feel free to post a comment here or over on FB. Over even on Amazon, as a comment on an extant review or in new review of your own. In a week or so I’ll go through all the various comments I can find, and pick someone to get a jar of my latest hot sauce (or something else if they don’t want that).
PS: there’s another new short review up on Amazon you might want to take a look at as well.
Filed under: Amazon, Brave New World, Carl Zimmer, Connections, Emergency, Feedback, Flu, General Musings, Health, Kindle, Marketing, Pandemic, Plague, Predictions, Preparedness, Promotion, Publishing, Science, Science Fiction, Society, Survival, The Loom, Umberto Eco, Writing stuff | Tags: Amazon, antibiotics, blogging, Carl Zimmer, Communion of Dreams, Darnell Sidwell, direct publishing, fire-flu, flu, influenza, jim downey, Kickstarter, Kindle, literature, norovirus, pandemic, predictions, promotion, science, Science Fiction, St. Cybi's Well, technology, Umberto Eco, virus, Wordpress, writing
So, the WordPress Machine informs me that I’ve had a fairly busy year blogging here.
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As I mentioned a while ago, earlier this month I had fallen prey to the nasty bit of cold virus going around. Turned out that the damn thing was even more stubborn for my wife, who is still struggling with a hacking cough and various other annoying symptoms. We’ve been keeping a close eye on it, watching for signs of secondary pneumonia, which would call for antibiotic intervention, but I think she’ll get past this on her own.
Which is good, because there really isn’t much we can do to fight a virus. In this sense, medical science is at about the same place in viral treatments as we were in dealing with bacterial infection 70 years ago:
In 1941, a rose killed a policeman.
Albert Alexander, a 43-year-old policeman in Oxford, England, was pruning his roses one fall day when a thorn scratched him at the corner of his mouth. The slight crevice it opened allowed harmless skin bacteria to slip into his body. At first, the scratch grew pink and tender. Over the course of several weeks, it slowly swelled. The bacteria turned from harmless to vicious, proliferating through his flesh. Alexander eventually had to be admitted to Radcliffe Hospital, the bacteria spreading across his face and into his lungs.
Alexander’s doctors tried treating him with sulfa drugs, the only treatment available at the time. The medicine failed, and as the infection worsened, they had to cut out one of his eyes. The bacteria started to infiltrate his bones. Death seemed inevitable.
* * * * * * *
You may not have heard much about it here, but the norovirus is causing all kinds of grief in the UK. Cases are up 83% over last year, and are estimated to have hit over a million people already. In the UK the norovirus is commonly called the “winter vomiting bug” whereas here we tend to call it “stomach flu”. As miserable as it makes people feel, it’s usually not a life-threatening disease for otherwise healthy people, and the best thing to do is just ride it out.
Of course, public health authorities have taken steps to try and limit the spread of the disease into populations where the virus could be life-threatening, and a lot of hospitals have curtailed or eliminated visiting hours. Furthermore, appeals have been made to the public to not to go see their doctors or go to emergency rooms for routine cases of the norovirus, since there is little that can be done to treat the virus and this just contributes to the spread of the disease.
Still, people get scared when they get sick, even when they know that it is a fairly common bug that’s going around — and one that most people have had before and gotten over just fine. So they tend to swamp available medical services, overwhelming the health care system.
Just think about what would happen if it was a disease which wasn’t known. And one which was killing people so quickly that they’d drop over in the street on the way home from work.
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But it is something which has had me in a bit of a quandary this fall, as I’ve been working on writing St. Cybi’s Well.
Howso? Well, because I kept going back and forth on making one final decision: where to end the book.
See, I know how the *story* plays out — I’ve had that all sorted since I first worked up the background for Communion of Dreams. But in going to write St. Cybi’s Well, I needed to decide exactly where in the story that book would end. Which is to say, I needed to decide how much, if any, of the onset of the fire-flu would be included. Because I could set everything up and have the book actually finish at the onset of the fire-flu — after all, the reader would know what was about to happen. Why drag the reader through that horror?
* * * * * * *
A week or so ago I made my decision, and I’ve been chewing it over since then as I’ve been busy with other things, making sure that I was comfortable with what I have decided, and why. I’m not going to give you the details, but you can safely assume from what I’ve said in this post that at least some of the pandemic will be portrayed.
I decided this not because I have a desire to write about the horror (in spite of what I may have said previously) but rather because it is critical for character development of the main character.
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So, the WordPress Machine informs me that I’ve had a fairly busy year blogging here. 293 posts (this makes 294), which is a faster pace than in some years. Of course, I’ve had a lot of promotional stuff do to with the launch of Communion of Dreams last January and everything to support that through the year, not to mention the Kickstarter for St. Cybi’s Well.
And while I’ve cautioned that I won’t be writing quite as much here on the blog as I’m working on St. Cybi’s Well, well, it does make for a nice change of pace.
So thanks for being along for the ride this year. Together we can see how things go in 2013.
Filed under: Connections, Emergency, Failure, Flu, Government, Health, Pandemic, Plague, Predictions, Preparedness, Science, Society, Survival | Tags: antibiotics, blogging, flu, health, jim downey, obesity, pandemic, plague, predictions, probiotics, science
Your body has something on the order of 10 trillion individual cells. But surprisingly, it has nine or ten times that number of microorganisms which it hosts in some capacity or another, many of which we have co-evolved with and which seem to be critical to our long health. While these microorganisms are typically much smaller than human body cells, in one very real sense, “you” is actually only about 10% “you.”
These microorganisms have a substantial impact on how your body digests food. On whether you can resist various kinds of infection or develop any of a range of auto-immune diseases. Perhaps even on your mood and risk assessment.
Would it therefore be any kind of a surprise at all if doing something to change the “mix” of these microorganisms had an impact on you?
Hell, it’d be a surprise if it didn’t.
Almost all of us know what happens when you have to take a broad-spectrum antibiotic: usually some degree of diarrhea and intestinal discomfort. And in the last decade or two it has become commonplace for people to seek out some variety of probiotics, frequently in the form of live yogurt, as a way to replenish gut flora following antibiotic treatment. I do it myself.
So, extending that idea a bit, researchers are now investigating whether part of the slow-moving plague of obesity can be due to the changes created in the human-hosted microorganisms:
The use of antibiotics in young children might lead to a higher risk of obesity, and two new studies, one on mice and one on humans, conclude that changes of the intestinal bacteria caused by antibiotics could be responsible.
Taken together, the New York University researchers conclude that it might be necessary to broaden our concept of the causes of obesity and urge more caution in using antibiotics. Both studies focus on the early age, because that is when obesity begins, the scientists say.
As I’ve noted previously:
In Communion I have a post-pandemic society, one which is recovering from a massive disruption caused by a flu virus which caused rapid death in a large percentage of the population. But the reality of what we’re dealing with might be even more insidious.
More insidious in this case because we have done it to ourselves.
And perhaps not even with direct antibiotic treatment to deal with some kind of life-threatening infection. Consider that it is still a widespread practice to boost livestock weight gain through the use of antibiotics, and that leaves a residue of antibiotics in the meat. If it boosts weight gain in feed animals, why wouldn’t it do the same to us?
I’ve said before that there has been some kind of change to the way our bodies absorb nutrients in the last 40 or 50 years, and that that is behind the global rise in obesity. Previously there were indications that it might be due to some kind of virus. Or an immune response to the germaphobia of the 20th century. But maybe it is more directly our own damned fault, and we’ve traded the ability to defeat infections for a different kind of health risk.
Filed under: Connections, Flu, Government, Health, NPR, Pandemic, Predictions, Science, Science Fiction, Society, Survival, tech, Writing stuff | Tags: avian flu, flu, H5N1, health, influenza, jim downey, NPR, pandemic, predictions, science, Science Fiction, technology
From the first page of Chapter 17:
“Sorry.” She looked over at him, the dread in her eye replaced by something else. “The 1918 flu was recreated in the early part of this century, as there was a growing concern about Avian flu. The scientists at the time discovered that the prevailing form of Avian Flu, the H5N1 virus, was surprisingly related to the 1918 pandemic virus. Almost identical RNA structure, similar DNA.”
“But you say this one is different.”
“Yeah. Ignis was such a nasty bug because it spread by aerosol, but it also had a very short incubation period, just a couple of days. Then the disease itself was very swift, and victims died within hours of onset. Like it was all time- compressed, hyper-virulent. This is one of the reasons that people thought then, and still debate now, whether it was a weaponized version of Avian flu.”
From yesterday’s All Things Considered:
Anyone and everyone can now look in the journal Science and read about how to make lab-altered bird flu viruses that have been at the center of a controversy that’s raged for months.
But in the eyes of some critics, the details of these experiments are effectively the recipe for a dangerous flu pandemic.
The H5N1 bird flu virus isn’t normally contagious between people, but these mutants most likely are. They were created with the best of intentions by a lab that’s trying to understand how flu viruses might change in the wild and start spreading in humans.
But as word of the experiments got out, scary headlines warned of a “doomsday” virus and a “super-flu.” Scientists, public health officials and security experts debated what to do in closed-door meetings, as others made their arguments in op-eds and at public meetings.
Remember when the “fire-flu” (Latin name: Ignis) was supposed to happen?
Draw your own conclusions.