Communion Of Dreams


Machado-Joseph Disease: I ain’t no wizard.

“Your love of the halflings’ leaf has slowed your mind.”

— Saruman, to Gandalf. The Lord of the Rings movie.

As I mentioned in my last post:

One of the problems that the industry has (at least in terms of medical use) is that the effects of cannabis are so varied, and standards so inconsistent, that pretty much the universal advice to new users is “just try a bunch of different things at small doses to figure out what works for you”.

So, following this standard advice, when I went to the dispensary for the first time I got a variety of different products. Tincture, edibles, flower, and a couple of pre-rolled joints. The tincture and edibles both have proven promising in my testing, taking the edge off my pain and other symptoms and helping me to sleep better. Last evening before dinner for the first time I tried to smoke some of the stuff taken from a pre-roll, so I could measure it out and be a little more careful about dosage than just lighting up a joint.

I measured out a modest amount, and put it in a glass pipe I’d also picked up. Standard little spoon-style, with a ‘carb‘ (hole on the side that controls airflow). I lit the bowl, drew the smoke into the chamber, and released the carb — and took a deep hit.

The smoke filled my lungs. And immediately I about coughed my lungs out. Hacking, spitting, coughing, tears, the whole 9 yards. Pathetic. But hey, I haven’t actually tried to smoke anything in what … four decades? But clearly, I ain’t no wizard. And I was overly generous in how much to put in the bowl.

Anyway, I went back inside after I recovered sufficiently, and sat down before the effects slammed into me. Good thing, because I was just about useless for the next twenty or thirty minutes. It wasn’t just the high, which I expected. It was also the way it seemed to suddenly multiply all the MJD symptoms I usually experience: vertigo, shaking hands, deep tremors in legs, shooting pain in the arms and feet, difficulty in eye-hand coordination, everything. All at once. About ten times worse than the usual symptoms.

I texted Martha and told her that she needed to take over dinner, that I just needed to sit and ride out the effects for an hour or so. I wasn’t worried; taking psychedelics long ago taught me how to just let the trip unfold without fighting it. The effects backed off and in an hour or so I was functional enough to get up and get some dinner, go into the living room and watch some TV while we ate. The effects then dropped off fairly completely after about four hours.

The worst thing, though? It didn’t do a damn thing for my pain. Oh well.

One strain down, others to try. But only after I get a small vape to allow me to control dosage even better, and take some of the edge off the raw smoke. Live and learn.

Jim Downey



Machado-Joseph Disease: testing time

So, late Wednesday FedEx delivered this:

That’s the sample collection kit for the MJD genetic test.

The paperwork included indicated that I could just take it to a local Quest Diagnostics and they would do the blood draw and send the samples off. I made an appointment for the next morning, and did just that. That done, now we just wait for the results. Ideally, I’ll get a copy of the results (I’ve formally requested one, and they should comply, since that’s part of the HIPPA guidelines) and not even have to meet with the Neurologists at the local large-institution university hospital which shall remain nameless. About the very last thing I want to do is deal with those people again. Yes, that experience has continued to annoy me.

And on that point, on one of my recent morning walks (I walk ~3 miles most mornings), I found myself walking with a couple of neighbors for part of the time. They were chatting about healthcare for another neighbor who was recently injured, and the conversation turned to the local large-institution university hospital which shall remain nameless. I mentioned that I’d recently had to deal with the Neurology Clinic there, and they both exclaimed words to this effect: “Oh, Jim, why the hell did you do that to yourself?!?!”

Yeah, the local large-institution university hospital which shall remain nameless has a bit of an image/reputation problem with the locals.

* * *

Late last week I also received my state Medical Marijuana card. I decided to apply for it, as part of my decision to be more active in managing my symptoms, whether they’re due to MJD or something else. Approval was all but certain, since on the ‘chronic pain’ criteria alone I qualified, having been on mild opioids for 10+ years. As I mentioned in one of my early posts about MJD, I’d noticed a persistent uptick in my use of my Rx pain meds (rather than just the occasional up and down variation I see over the months), particularly to aid in sleeping. Symptoms like Restless Leg/Arm Syndrome tend to disrupt my sleep in the early morning hours, contributing to spiraling problems associated with lack of sleep.

So I wanted something to help me sleep, without increasing my use of opioids or getting into a cycle of taking additional Rx meds. Many of my friends who deal with chronic pain has found MMJ (Medical MariJuana) to be efficacious in dealing with sleep problems, so I figured it was worth a try.

Let me tell you, there’s nothing like going to a medical cannabis dispensary for the first time to make one feel *REALLY* old and out-of-touch. Seriously, I gave the budtender a nice tip not only for his assistance, but also for not calling me “Gramps”.

The whole experience was a little overwhelming, even though I had done my research and spent a fair amount of time exploring products on the dispensary’s website. It’s clear that this is still an immature industry, figuring out how to do branding/marketing, communicating with different clienteles, tapping into demographic groups who are not already savvy about cannabis use.

But I was able (with the help of the budtender) to select some different products to try. One of the problems that the industry has (at least in terms of medical use) is that the effects of cannabis are so varied, and standards so inconsistent, that pretty much the universal advice to new users is “just try a bunch of different things at small doses to figure out what works for you”.

So that’s what I’m doing at present. So far, it looks promising.

* * *

Not all the tests we face in life are big. Or obvious. Or dramatic.

Sometimes they’re just a simple challenge: how to deal with this small problem. How to help someone. How to get through the day, or night.

With luck, in another couple of weeks I’ll have more information about my MJD status, and know whether and to what degree I have the disease. I was always very good at taking tests in school, and those I’ve faced in my life since I like to think I’ve passed reasonably well.

Waiting is hard. But it is just one more test to manage, piece by piece, day by day.

Jim Downey



A path out of darkness.

As I’ve noted previously, I’m mildly bipolar, with my ‘natural’ bipolar cycle running about 18 months. I had noticed the start of a psychological downturn three or four months ago, following the intense boost that came with the discovery and correction of my cardiac artery blockage and subsequent recovery. Since I don’t usually realize that I have taken a downturn until it has gone on for a while, I’m guessing that I’m approaching the bottom of the cycle.

* * * * * * *

Some 50 years ago, my father-in-law (who I never met — he passed away before my wife and I knew each other) put in a simple brick walkway around two sides of his garden. OK, that doesn’t sound like too big a deal. But his garden was almost a full acre in size, and the walkway more than 100 yards in length. Yeah, it really is that long.

After his death, the garden was reverted back to lawn. And slowly the brick walkway was reclaimed by that lawn.

But since the house remained in the family, memory of the walkway wasn’t lost. Some time back the walk was uncovered, and for the last decade or so we did a pretty good job of keeping it clear and used. Here’s a pic of some of it:

20160905_093857

Note the box turtle in the patch of sunlight in the upper part of the pic.

* * * * * * *

I sent this in a message to a friend this morning who had asked if I was feeling more healthy these days:

Maybe?

I do feel a lot stronger and more … vital. But I really don’t want to be one of those ’50-something year old guys who discover the power of exercise!’ At best, it’s annoying to most people. At worst, it’s obnoxious able-ism. My situation, both my peculiar genetic problem and my lifestyle permitting me to get a LOT of exercise time in, is extremely unusual, and not something I can claim as being due to my own effort.

Yeah, I think a lot about this.

* * * * * * *

For a couple of years we’ve talked about rebuilding the brick walkway, because while we’ve been able to keep it uncovered, it is nonetheless ‘sunk’ relative to the surrounding lawn. Meaning that it collected grass clippings and mud, tended to puddle, and retained ice and snow for a prolonged period. Plus there were sections which had been damaged by construction and heavy  trucks which came into the yard to do utility and tree work.

But redoing a 300’+ length of brick walkway is no small task. To do it correctly would require a lot of work and a fair amount of expense for proper landscape edging, landscape fabric, gravel/chat, and sand. And if we were going to go to the trouble of redoing it, we wanted to do it correctly and expand it a bit.

About two weeks ago we ordered the first four cubic yards of chat, got some of the other materials, and got started. Since the edging material we’re using comes in 60′ lengths, we decided to use that as the operative size of each ‘section’ of the walkway. The first step was to remove the old brick walk:

20160907_114300

Then expand the bed, take it down, and level it out:

20160911_153047

Then put down the base layer of chat on top of the landscape fabric:

20160912_110315(That’s about 10,000 pounds of chat, by the way.)

And then start putting down brick. Here’s how far we’ve gotten as of yesterday afternoon:

20160917_135339

With luck, we’ll finish getting the rest of the bricks laid in this ‘section’ today or tomorrow. Then we’ll be about one-fifth through the whole project.

* * * * * * *

As I’ve noted previously, I’m mildly bipolar, with my ‘natural’ bipolar cycle running about 18 months. I had noted the start of a psychological downturn three or four months ago, following the intense boost that came with the discovery and correction of my cardiac artery blockage and subsequent recovery. Since I don’t usually realize that I have taken a downturn until it has gone on for a while, I’m guessing that I’m approaching the bottom of the cycle.

One of the things I learned long ago is that doing something constructive helps me cope with the depressive part of my bipolar cycle. By focusing on something in discrete chunks, I can slowly ‘walk’ out of my depression, since I can see tangible progress happening on something.

We probably won’t be able to finish the full 300’+ of the brick walkway before winter sets in. But that’s OK. Being able to spend a couple of hours working on the walk each day (when the weather permits) helps. It’s good exercise for my body. And it helps to keep my mind from falling too far into the darkness.

 

Jim Downey



Building a better human.

From Chapter 5 of Communion of Dreams, after the revelation that the Chinese orphan Chu Ling is a clone:

Jon looked around. He decided to tell them the rest of the bad news. “And that’s not all. There’s evidence that the original host had been genetically manipulated to radically change several characteristics related to intelligence.”

Bailey looked a little confused. “What’s that mean?”

Gish sighed. “It means that someone has created a better human, and now is producing copies.”

“Well, better in their eyes, anyway,” said Gates. Her voice contained a touch of bitterness.

 

Gee, here’s a bit of news:

Chinese scientists create first genetically modified human embryos

And so it has come to pass: Chinese scientists at the University in Guangzhou have created the first genetically modified human embryos. Although there had been rumors circulating for some time that it had already been done, until now, there has been no official scientific report.

 

Another prediction come true.

 

Jim Downey



Scraping by.

I’ve been entirely preoccupied with a big book conservation project which landed in my lap unexpectedly and needed attention right away (and trying to keep work going on St. Cybi’s Well), but a news item I saw the other day has been kicking around in my head. Er, so to speak. It’s the notion that the quality of dental hygiene & health in the modern era is *much* worse than it was before the advent of civilization. Here’s a good passage from one of the better articles which sums this up:

Our mouths are now a gentrified shadow of their former selves. And as Carl Zimmer described earlier this week, ecosystems with an impoverished web of species are more vulnerable to parasites. He was writing about frogs and lakes, but the same is true of bacteria and mouths. The narrow range of microbes in industrialised gobs are more vulnerable to invasions by species that cause disease, cavities, and other dental problems.  “As an ecosystem, it has lost resilience,” says Cooper. “It basically became a permanent disease state.”

Of course, current thinking is that this is due to a fairly radical change in diet between the two time periods, with our reliance now on domesticated grain crops.

But I know the real reason:

“He had a nutty theory that early man had been shortlived, but impervious to disease. Something about being able to trace back mutation clues to some proto-genes that suggested a powerful ability to heal.” Jackie frowned.

Yeah, that’s from almost the end of Communion of Dreams. And is a topic we’ll revisit in the prequel.

Hehehehehehehe.

 

Jim Downey



We are the champions.*

From BoingBoing here’s an embedded video of a long (90 minutes) but *really* fascinating discussion on the topic of why homo sapiens is the sole surviving member of our genus, and what that might tell us about ourselves. What I very much enjoyed was the way the different disciplines brought their own perspective to the question, and how each different perspective tends to reinforce the science of the others.

Why did our species survive?

Today, we’re the only living member of the genus Homo and the only living member of the subtribe Hominina. Along with chimpanzees and bonobos, we’re all that remains of the tribe Hominini.

But the fossil record tells us that wasn’t always the case. There were, for instance, at least eight other species of Homo running around this planet at one time. So what happened to them? What makes us so special that we’re still here?

* * * * * * *

From Chapter 5:

Navarr turned and looked at Jon. “Any indication from the medical report what the genetic changes mean functionally?”

“No, not yet. The way that the genetic manipulation will play out is very difficult to predict, since that is a subtle and complex dance over time. They have simulations running now, and we may have an idea in a few days.”

* * * * * * *

I don’t want to give away too much, but there are other intimations in Communion of Dreams on this topic, since it is one which has long intrigued me. And while I am nowhere near knowledgeable enough to get too far into the molecular genetics, the current state of the science is such that there is room for plausible speculation.

And again, without giving too much away, I can say that this is something which will be one of the themes in St. Cybi’s Well.

* * * * * * *

Speaking of giving things away: next Saturday, June 9th, will be a Kindle promotional day for both Communion of Dreams and Her Final Year. As previously, the Kindle edition of each book will be available for free download all day, and you don’t even need to own a Kindle to get & read your free copy, as there is a free emulator app for just about every computer/tablet/mobile device out there.

In addition, I will be offering a signed paperback copy of each book as a prize — details to be announced in a couple of days!

Jim Downey

*of course.